GZMB anticorps

N° du produit ABIN7605016

L’anticorps Lapin Monoclonal anti-GZMB a été validé pour IHC, IF, IP et ICC. Il convient pour détecter GZMB dans des échantillons de Humain.

Aperçu rapide pour GZMB anticorps (ABIN7605016)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: AAHC-7

Détail du produit anti-GZMB anticorps

Fonction: Anti-Granzyme B GZMB Monoclonal Antibody

Attributs du produit: Anti-Granzyme B GZMB Monoclonal Antibody (ABIN7605016). Tested in IHC, ICC/IF, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Granzyme B This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: GZMB

Sujet:

Synonyms: Leptin receptor,LEP-R,HuB219,OB receptor,OB-R,CD295,LEPR,DB, OBR,

Tissue Specificity: Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.

Poids moléculaire: 23 kDa

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis